Clinical Questions
How does Saxum Durum Ready work?
Saxum Durum Ready contains a class of medications called PDE5 inhibitors, which work by dilating blood vessels and increasing blood flow to the penis, making it easier to get and maintain an erection.
Mechanism of action of Saxum Durum Ready
An erection is a physiologic body process in which the penis becomes engorged with blood. The mechanism of obtaining an erection is initiated by sexual stimulation. This leads to the release of nitric oxide (NO), which acts on the smooth muscle of the penis. NO stimulates an enzyme called guanylate cyclase, which mediates the conversion of GTP to cyclic GMP (cGMP). cGMPcauses smooth muscle relaxation and blood vessel dilation within the penis, which increases blood flow.
Phosphodiesterases are the enzymes responsible for degrading (breaking down) cGMP. The medications that are in Saxum Durum Ready (sildenafil and tadalafil) are phosphodiesterase type 5 (PDE5) inhibitors. Inhibiting PDE5 increases the amount of available cGMP, thus increasing smooth muscle relaxation and blood vessel dilation, increasing blood flow into the penis, and resulting in an erection.
How long does Saxum Durum Ready take to start working?
Due to Saxum Durum Ready being directly absorbed under the tongue, it typically starts to work in 15 minutes or less. For best results we recommend taking Saxum Durum Ready at least 30 minutes prior to sexual activity.
How long do the effects of Saxum Durum Ready last?
The effects of sildenafil generally last 4-5 hours, while the effects of tadalafil typically last for 24-36 hours. Using this medication with liver or kidney disease may increase the time that this medication remains in the body and we recommend consulting with your doctor prior to use. Concurrent use of certain medication may also prolong the effects or cause adverse effects. Please see the below question regarding medication interactions.
What are the common side effects?
- Headache
- Flushing
- Rash
- Cyanopsia (blue-tinted vision)
- Mild blurred vision
- Indigestion
- Irritation of the skin within the mouth and under the tongue
- Nasal Congestion
- Nausea
- Back Pain
- Muscle pain (myalgia)
- Dizziness
If you experience any of the following stop taking Saxum Durum Ready and seek medical care immediately.
- Chest pain
- Dizziness or Syncope (fainting)
- An erection lasting longer than four hours
- Any sudden changes in hearing or vision
- Allergic Reaction (swelling of the face and lips, wheezing, sensation of throat closing, difficulty breathing, rash)
- Serious Skin Reactions (rashes, blistering, peeling)
Can I take this with other medications?
Saxum Durum Ready can interact with other medication you may be taking. Make sure to be honest and thorough with your doctor during the medical survey to avoid any adverse effects.
- Medications containing any nitrates (such as nitroglycerin, isosorbide mononitrate or isosorbide dinitrate), nitrites or alkyl nitrites (also known as “poppers” or “rush”), as well as guanylate cyclase (GC) stimulators (such as riociguat or Adempas) must NOT be used at the same time as Saxum Durum Ready, as this combination may lead to a dangerous drop in blood pressure and/or syncope (fainting).
- Revatio (sildenafil) is a medication prescribed for pulmonary hypertension. Do not take Saxum Durum Ready if you are prescribed Revatio (sildenafil)
- Do not take with any illegal drugs
- AVOID grapefruit, grapefruit juice and excessive alcohol consumption when taking Saxum Durum Ready.
- Use caution when taking Saxum Durum Ready with alpha-blockers or anti-hypertensive (blood pressure) medications, as this may lead to a drop in blood pressure and/or syncope (fainting).
- Use caution when taking Saxum Durum Ready with strong CYP inhibitors (such as ritonavir, saquinavir, ketoconazole, itraconazole, erythromycin), as Saxum Durum Ready metabolism is decreased, and this may lead to a prolonged erection, a drop in blood pressure and/or syncope (fainting).
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Saxum Durum Ready can interact with the following commonly prescribed medications. This is not an all-inclusive list. Be sure to include all medications that you take in the patient survey. If your medication list changes be sure to message your doctor.
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Nitrate-containing medication
- nitroglycerin (Gonitro, Nitrolingual, NitroMist, Nitrostat)
- isosorbide mononitrade (Imdur, Ismo, Monoket)
- isosorbite dinitrate (Dilatrate-SR, Isordil, Isordil Titradose)
- nitrites or alkyl nitrites known as “poppers” or “rush”
- Revatio (sildenafil)
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Guanocyclase stimulators
- riociguat (Adempas)
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Alpha blockers
- alfuzasin (Uroxatral)
- doxazosin (Cadura)
- dutasteride and tamulosin (Jalyn)
- prazosin (Minipress)
- silodosin (Rapaflo)
- tamulosin (Flomax)
- terazosin (Hytrin)
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Protease inhibitors
- atazanavir (Reyataz)
- darunavir (Prezista)
- fosamprenavir (Lexiva)
- indinavir (Crixivan)
- lopinavir/ritonavir (Kaletra)
- nelfinavir (Viracept)
- ritonavir (Norvir)
- saquinavir (Invirase)
- tipranavir (Aptivus)
- atazanavir/cobicistat (Evotaz)
- darunavir/cobicistat (Prezcobix)
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Antifungal medications
- ketoconazole (Nizoral)
- itraconazole (Sporanox)
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Antibiotics
- clarithromycin (Biaxin)
- telithromycin (Ketek)
- erythromycin
- All blood pressure medications can potentially cause an unsafe drop in blood pressure when used with Saxum Durum Ready and should be included in your medication list.
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Nitrate-containing medication
What if I have other medical conditions?
Your doctor will review all the information that you provide in your health questionnaire before determining if Saxum Durum Ready is right for you. So, it is important that you are detailed and honest in your responses. If you have questions about your medical history, please consult your primary care physician.
Is it safe to take sildenafil and tadalafil together?
Yes, these medications can be safely combined together so long as they are prescribed by a licensed physician who has thoroughly reviewed your medical history and will continue to closely monitor your care.
Can I take Saxum Durum Ready while drinking alcohol?
Our doctors recommend you do not take Saxum Durum Ready when you will be drinking heavily.
Can I take Saxum Durum Ready while using other illicit drugs?
Our doctors recommend you do not take Saxum Durum Ready while engaging in illicit drug usage.
Can I smoke/vape while taking Saxum Durum Ready?
Our doctors recommend you wait at least 30 minutes after taking Saxum Durum Ready to smoke/vape. This is because smoking may affect the absorption of the medication.
Will Saxum Durum Ready help me last longer?
Saxum Durum Ready contains PDE5 inhibitors, which have been shown in studies to be an effective treatment for premature ejaculation. It may also help decrease the amount of time it takes for you to obtain additional erections.
Does your product increase sensitivity?
Saxum Durum Ready can help you get and maintain an erection. A strong erection can help increase sensitivity. However, the product itself does not affect sensitivity of the penis.
Will it get me hard?
Saxum Durum Ready can help you initiate and maintain an erection. It will feel harder because the medication works to dilate blood vessels which will cause more blood flowing into the penis.
If Viagra and Cialis didn’t work for me will Saxum Durum Ready?
Saxum Durum Ready combines both sildenafil and tadalafil, which are short and long acting PDE5 inhibitors. Because the medication dissolves under the tongue, it increases absorption into the bloodstream, making it work faster. Furthermore, our physicians can tailor doses specifically to each patient’s need. We cannot promise it will work for everyone, but our doctors will work for you to try to deliver optimal results while helping limit side effects.
I usually take tadalafil low dose every day, can I take Saxum Durum Ready every day?
No, Saxum Durum Ready is not a daily medication. It should only be taken as needed per the instructions on your prescription.
The maximum recommended dosing frequency of Saxum Durum Ready is one dose in every 24 hours. For Saxum Durum Ready combinations that contain greater than 10mg of tadalafil, it should be noted that tadalafil can stay in the blood stream for up to 36 hours, and this should be taken into consideration.
I have taken Viagra/Cialis before and I have experienced side effects. Will I experience the same side effects with Saxum Durum Ready?
Saxum Durum Ready contains the same active ingredients as both Viagra and Cialis, so you may experience similar side effects. However, our doctors will work with you to try to
find the best treatment and dosage to help limit side effects while maintaining effectiveness.
Be sure to explain to your doctor in the questionnaire if you had a previous side effect or drug reaction from Viagra or Cialis. If you have any other questions do not hesitate to message your doctor.
What strength should I choose?
Our product selection page will provide you with some general advice to help get you started. Your doctor will review your request and only approve it if he/she feels it will be a safe and effective treatment option for you. When in doubt, it is always better to start at a lower dose and increase as needed. If our physicians require more information, they will contact you.
What is APO?
APO is a dopamine promoter. It activates the dopamine receptors in the brain to create erections by priming the brain for sexual arousal. It’s not an analgesic (pain reliever). Other uses include treatment for Parkinson’s Disease. May cause drowsines
Can I speak directly to a doctor?
After signing-up and completing the questionnaire, you can message your doctor at any time through the INBOX in your secure Member portal.
Can females use Saxum Durum Ready?
No, Saxum Durum Ready is not intended for female use.
Will Saxum Durum Ready prevent pregnancy or protect me from sexually transmitted infections?
No, Saxum Durum Ready will not prevent pregnancy or protect from sexually transmitted infections.
What are other things that I can do to improve my sexual function
Sexual function (obtaining and maintaining an erection) is a multi-faceted body process. Saxum Durum Ready works by increasing blood flow to the penis and thus increasing the ability to obtain and maintain an erection. Increasing overall health and wellbeing can also improve sexual function. This includes maintaining a healthy body weight, exercising and smoking cessation. Maintaining tight control of chronic disease processes such as high blood pressure and diabetes can also improve sexual function. Although we do not treat these diseases at Saxum Durum, we recommend working closely with your primary care physician in order to optimize your overall health and thus improve your sexual function.
Non-Clinical Questions (Product)
What is Saxum Durum Ready + APO?
Saxum Durum Ready is a fast-acting, long-lasting E.D. medication combining the active ingredient in Viagra (sildenafil) and Cialis (tadalafil). It also includes APO, a dopamine promoter that primes the brain for arousal. Saxum Durum dissolves under your tongue, bypassing your liver and stomach, which creates a fast onset.
Saxum Durum Ready contains the same active ingredients as Viagra and Cialis, but you claim that it works faster. How is that possible?
Saxum Durum Ready works faster than Viagra/Cialis pills because it dissolves under your tongue and is absorbed directly into your bloodstream.
What does it taste like?
Saxum Durum Ready has a strong fresh mint flavor, like a breath mint.
How long does it take to dissolve?
It varies from person to person but on average Saxum Durum Ready takes about 11 minutes to dissolve.
Does Saxum Durum provide a moneyback guarantee?
Because Saxum Durum Ready is a prescription medication and custom made for each patient, it is non-refundable. If you’re unhappy with the product, please reach out to customer care by calling 1-888-871-7942 or emailing us at [email protected].
IS Saxum Durum Ready + APO NATURAL?
Saxum Durum Ready + APO is a fast-acting, long-lasting E.D medication combining the active ingredient in Viagra (sildenafil) and Cialis (tadalafil). It also includes APO, a dopamine promoter that primes the brain for arousal. Saxum Durum dissolves under your tongue, bypassing your liver and stomach, which creates a fast onset.
The color of my Saxum Durum Ready is dark green/black, in the advertising it is a blue square. Is it safe to take?
The blue square in the advertising is for the photography. The sublingual does not contain any ingredients, so it gives a blue color. Once the ingredients are added, because some of them are beige it changes the color of the finished product to dark green. That is the actual color of the medication and it is safe to take.
Ordering
How do I order Saxum Durum Ready?
Order online by going to SAXUMDURUM.COM. Click sign-up and follow the on-screen prompts.
Order over the phone by calling 1-888-871-7942
*Whether you plan to order online or over the phone, please have the names of any medications you’re taking, a recent photo of just yourself, and a photo ID ready.
How long does it take to receive my order?
Saxum Durum ships within 48 hours after your order is processed, depending on the day you order.
New Members: The doctor will take 24 hours to prescribe before processing. If the doctor has any questions, there will be a delay.
Florida Residents: We ship Mon-Thurs. Fridays are possible if UPS offers Saturday delivery to your area.
All Other States: We ship Mon-Wed. Thursdays are possible if UPS offers Saturday delivery to your area.
*If you are expecting a Saturday delivery, but UPS is unable to fulfill it, you will get your order on Monday
Will a doctor contact me?
A doctor will review your health questionnaire and requested dose strength within 24 hours of placing your order. If your doctor requires additional information, you will be contacted. *Please note, your order may be delayed until your doctor receives all necessary information.
How do I know the date of my next refill?
Log into your member portal and select “ORDERS.” See the date of your last order, and your next autofill will be processed 48 hours before the next due date.
*Example: if your last order was on 01/15/2021, your next autofill will be processed on 02/13/2021 (48 hours before the refill due date of 02/15/2021)
Can I pay by insurance?
Saxum Durum Ready is a compounded medication which are not covered by medical insurance.
ID
Why do you need an ID and photo?
DEA and State Medical Boards require these forms of ID before we can prescribe you any medications.
*If you have any trouble uploading your photo or copy of your ID, please contact the Customer Care team by calling 1-888-871-7942 or emailing us at [email protected]
Subscription
Is Saxum Durum Ready a subscription service
Yes, Saxum Durum Ready is a subscription service. However, after you sign up and receive your first order, you can pause your subscription at any time.
How do I update my payment information?
Log into your Member portal and select the “Edit Profile” option to view past orders, order status, and payment.
How can I see what I have ordered before?
Log into your Member portal and select the “My Orders” option to view past orders, order status, and payment.
How much does Saxum Durum Ready + APO cost?
MAX STRENGTH $140
Si 110mg + Ta 22mg + APO 3mg
MOST POPULAR $120
Si 80mg + Ta 22mg + APO 3mg
MEDIUM STRENGTH $100
Si 65mg + Ta 22mg + APO 2mg
LOW STRENGTH $80
Si 40mg + Ta 14mg + APO 2mg
Members who subscribe to the 90-day plan, or have an active 30-day subscription, get FREE shipping. Plus, 90-day subscribers save $70 on every order.
Shipping costs $10 for those who choose a one-time purchase, or have paused a 30-day subscription plan. All subscribers get a FREE consultation.
Can I order just one pack to try it out?
There is a one-time purchase option available at check out.
How do I place a new order?
Log into your Member portal and select the “Order Now” option.
How do I request a refund?
Because Saxum Durum Ready is a prescription medication, we cannot provide refunds on orders. If you’re unhappy with the product, please contact customer care and we’ll do our best to remedy the issue.
How do I know the date of my next refill?
Log into your Member portal and select “My Orders” to see the date of your last order, and your next autofill will be processed 48 hours before the next due date.
*Example: if your last order was on 01/15/2021, your next autofill will be processed on 02/13/2021 (48 hours before the refill due date of 02/15/2021).
If you do not wish to process your next refill, you must pause your subscription at least 48 hours before your next refill date. Once the order is being processed, it cannot be cancelled or refunded.
HOW DO I CANCEL MY ORDER?
To cancel your order before the doctor has begun the consultation, login to the Members Portal and click ‘Cancel Order’. If the doctor has already begun or finished the consultation, please contact Customer Care. It’s a time sensitive request, so please act promptly.
1-888-871-7942 / [email protected]
8am – 8:30pm CT Mon-Fri
9am – 1pm CT Sa
To pause your subscription…
- 1. Log into your Members Portal.
- 2. Go to ‘My Subscription’.
- 3. Click ‘Change Subscription’.
- 4. Click ‘Pause Subscription’.
- 5. Select a reason for pausing your subscription.
- 6. Click ‘Submit’.
Shipping
Is Saxum Durum Ready + APO available in my state?
Saxum Durum is currently available to ship to the following states: AL, AZ, AR, CA, CO, CT, FL, GA, HI, IL, IA, KY, LA, ME, MD, MA, MI, MN, MO, NE, NV, NJ, NM, NY, NC, OH, OK, OR, PA, RI, SD, TN, TX, VT, VA, WA, WV, WI & WY.
Also available to ship to Washington D.C.
How long does it take to receive my order?
Saxum Durum ships within 48 hours after your order is processed, depending on the day you order.
New Members: A Saxum Durum doctor will review your health questionnaire within 24 hours to determine if Saxum Durum Ready is right for you. Once reviewed, if no other information is needed by your doctor and a prescription is approved, then your order will be processed immediately. Please make sure to provide all necessary information to avoid delays.
Florida Residents: Mon-Thurs. Fridays are possible if UPS offers Saturday delivery to your area.
Other States: Mon-Wed. Thursdays are possible if UPS offers Saturday delivery to your area.
*If you are expecting a Saturday delivery, but UPS is unable to fulfill it, you will get your order on Monday.
What shipping courier do you use?
Saxum Durum uses UPS Ground for Florida, UPS Air for the other mainland states, and Fed Ex for Hawaii.
How do I receive tracking information for my shipment?
To track your order…
An email is sent to you once the tracking number is created. Don’t see it? Check your spam/junk folder. Sometimes it mistakenly lands there.
You can also track your order by logging in to your Members Portal and checking the Status Bar at the top of the page.
Do you use discreet packaging?
Your order will arrive in a UPS branded Express Box with the name of the pharmacy on the label. There is no Saxum Durum branding on the shipping container.
My order is in transit and I need to change/correct my delivery address
To redirect your package, go into the tracking reference. Then select and register with UPS Choice. Once registered with UPS Choice and logged in, there will be an option to redirect.
I have a problem with my delivery
Call or email our Customer Care Team 1-888-871-7942 / [email protected] Mon – Fri 9-7pm EST.
Packaging/Storage
My order came with ice packs. Do I need to freeze it?
Do not freeze your Saxum Durum Ready. Your package ships with ice packs because temperatures in transit may exceed 74 degrees. Store at room temperature or in your refrigerator.
My Saxum Durum Ready arrived melted
Please call or email our Customer Care Team 1-888-871-7942 / [email protected] Mon – Fri 9-7pm EST.
How do I store Saxum Durum Ready?
Saxum Durum Ready should be stored at room temperature 74F or in the refrigerator. Do not freeze Saxum Durum Ready. We ship with ice because temperatures in transit can increase above 74F, the ice packs help to maintain the quality of the product in transit.
Legitimacy
Where is Saxum Durum Ready made?
Saxum Durum is made in a USA-licensed compounding pharmacy using ingredients from vetted, high-quality sources. Our HQ is based in Austin, Texas.
How long has Saxum Durum been around?
We have been doing R&D on Saxum Durum Ready for about 6 years. We launched under the Saxum Durum brand in 2020.
Technical Problems
Having trouble logging in to your account?
- Go to Members
- Check that you are entering the correct email and password.
- Reset your password by selecting Forgot Password, and following the steps listed.
If this does not work:
- Delete cache in your browser or delete browsing history and try again.
- Try to log in from a different browser or a different device.
If these suggestions do not work, call our Customer Care Team for assistance 1-888-871-7942 Mon – Fri 9-7pm EST.